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Spontaneous Remission of a Third-Nerve Palsy in Meningeal Lymphoma Ann Neurol 32:100-102, Galetta,S.L.,et al, 1992 See this aricle in Pubmed Article Abstract We report on a patient with spontaneous remission of a third-nerve palsy who was subsequently found to have meningeal lymphoma.Initial magnetic resonance images(MRI)showed bilateral enhancement of the third nerves. Follow-up MRI 7 months later,without treatment,showed complete resolution. One year after initial presentation,the patient developed multiple lumbosacral radiculopathies and examination of a nerve root biopsy specimen disclosed a B-cell lymphoma.Serial cerebrospinal fluid analyses over the previous year showed occasional atypical cells,later found to resemble closely the biopsy cell type.We conclude that meningeal lymphoma may have a protracted course,with spontaneous remission of both clinical and neuroimaging findings.

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